What airlines use Boeing? Major carriers like Southwest Airlines, Alaska Airlines, and United Airlines are among the leading operators of Boeing aircraft. Southwest relies entirely on the 737 series for its operations, while Alaska Airlines incorporates the Boeing 737 and 737 MAX for its regional and international routes. United Airlines’ fleet includes multiple Boeing models, from the 737 for short flights to the 787 Dreamliner for global destinations. Boeing’s versatile designs make it a top choice for these airlines.